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Vitamins

Vitamins

Vitamin E
  • Turn-around time = 5 to 7 days.
  • Specimen required is 0.5 mL of serum protected from light and shipped in an amber plastic tube.

Vitamin E is a fat-soluble vitamin. There are eight forms of vitamin E, however, the most biologically active form is d-alpha-tocopherol. The best defined role for vitamin E is an antioxidant for unsaturated fatty acids in cell membranes. It is also important in energy metabolism and synthesis of RNA, DNA, and red blood cells. It acts as an antioxidant in the lungs against smog. Vitamin E is absorbed in the presence of bile in the small intestine. Deficiency of vitamin E may result in hemolysis of RBCs, sterility, higher risk for heart disease and stroke.

The RDA is 22 I.U. A suggested supplemental range is 100 to 1000 I.U. A toxic range has not been established, but 4000 I.U. and higher should be taken with caution.

The methodology is by HPLC. The normal range established in our laboratory is 0.6 to 2.7 mg/dL.

Selected References:

  1. Tietz Textbook of Clinical Chemistry, 3rd ED., 1999, Saunders Company;p1005-6.
  2. McCormick DB, Wright LD., Eds.: Vitamins and coenzyme. Methods in Enzymology. Vol. 18, part C. New York, Academic Press, Inc., 1971.

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