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Chelation

Profiles

Trace elements- Urine Post Chelation

  • Turn around-time = 5 - 7 days
  • A 24-hour urine test for measuring nutritional and toxic mineral (elements) after I.V. treatment with EDTA. These results are usually compared to the pre-chelation results.

The profile includes aluminum, cadmium, calcium, chromium, copper, iron, lead, magnesium, manganese, and zinc. The post chelation 24-hour collection begins at the same time as the I.V. chelation therapy is started. Patients must empty bladder immediately prior to IV. Urine must be collected for a full 24-hour period-including during the IV therapy. Patient should note time and date of last urination for an accurate 24-hour urine collection. The collection container is a one-gallon mineral-free amber plastic jug. This may be requested from the BioCenter Laboratory. A mineral-free cup may be used to catch urine and then be poured into the gallon jug. Do not rinse the cup between collections as tap water may contain trace minerals. Seal the cup with the mineral-free plastic lid between collections. NOTE: the collection jug must be refrigerated.

If for some reason the patient is unable to collect the specimen for a full 24-hours, note the length of time of collection on the requisition slip. Mix the collection jug vigorously before pouring an aliquot of 150 mL (about ½ a cup) into the transport container. Refrigerate or freeze the container for transport.

A sample will be rejected if the total 24-hour urine volume is not noted on the requisition or if non-mineral-free containers are used for collection and transport. The elements are measured by ICP/atomic absorption method.

References are furnished upon request.

Trace Elements – Urine, Pre & Post collection

See instructions for Post chelation. For pre collection, the 24-hour period begins immediately after the patient has urinated to empty his/her bladder. This first urination specimen is not collected. It is discarded. Subsequent urination specimens are to be collected for testing.The patient should use the same collection technique and containers as described for post chelation. Note the time and date in order to collect the urine for a full 24-hour period. Urine must be collected for a full 24-hour period prior to having the EDTA administered to the patient.

The levels of the toxic elements (aluminum, cadmium and lead) as well as the nutrient elements (calcium, chromium, copper, iron, magnesium, manganese, zinc) in the post chelation are compared to the pre chelation levels.

If doing a pre and post within a short period of time, both samples can beproperly labeled and submitted together.

References furnished upon request.

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