Miscellaneous Tests ASO CEA Coenzyme Q10 Creatinine DHEA-S H. Pylori Antibody Histamine Homocyst(e)ine Polyamines PSA

Homocyst(e)ine Turn-around time = 5 to 7 days. Specimen is 1.0 mL of EDTA plasma. Homocyst(e)ine (NOT homocystine) is an intermediate in the synthesis of cysteine from methionine, via cystathionine. Deficiency of vitamins B12, B6 and/or folic acid can affect the enzyme pathways associated in the formation of cysteine, resulting in an elevated homocysteine in the blood. Numerous studies have shown an association between elevated levels of blood homocysteine and various vascular and cardio-vascular diseases. It is thought that homocysteine may act as a molecular abrasive damaging the inner layer of blood vessels causing an atherosclerotic lesion. Increased levels of homocysteine have been associated with advanced age, hypothyroidism, impaired renal function, and SLE. Medications known to elevate homocysteine are nicotinic acid, L-DOPA, theophylline and methotrexate. Methodology for homocysteine is by Fluorescence Polarization Immuno Assay (FPIA). Reference values established in our laboratory are 5 to 15 umol/L Selected References: Clarke R., Daly L., Robinson K., et. al. Hyperhomocysteine: An independent risk factor for vascular disease. N Engl J Med, 1991, 324:1149-55. Caffaneo, M. Hyperhomocysteine, Atherosclerosis and Thrombosis. Thromb Haemost, 1998, 81:165-76. Herman, W. The importance of hyperhomocysteinemia as a risk factor for diseases: an overview. Clin Chem Lab Med, 2001, 39(8):666-74. Back to Miscellaneous Lab Tests Home Page

---

[Search] [Home] [About Us] [Why Bio-Center?] [Lab tests] [Order Test Kits] [FAQ] [Contact Us]

---

Back To Bio-Center Lab

This website is managed by The Center For The Improvement Of Human Functioning International
A Non-profit Medical, Research and Educational Organization
3100 North Hillside Avenue, Wichita, KS 67219 USA
Phone: 316-682-3100; Fax: 316-682-5054
© (CIHFI) 2008

This website and all contents are Copyright: 1997/2008 CIHFI - All Rights Reserved.